I read alot about Joomla and Nginx but I rarely see a web site that actually uses that combination. I guess that the main reason is simplicity of Joomla and the fact that you can run it on almost every environment that shared hosting providers offer these days
I'm running a server with nginx+php-fpm and it is crazy fast. Not running joomla though, and I also am a bit interested in what other people joomla/nginx experiences are.
I want to try running joomla on nginx, but I'm worried about the lack of modsec. Read something about naxsi, but I wasn't able to try it out.