Not really. To use a block variation you go to the layout of your outline and then click on the particle setings that you wish to change, then click on the "block" tab and start typing the block variation in the "block variation" field and a dropdown will appear allowing you to choose the one that you want.
For typography classes you just use those in your html as a class name
<p class="alert alert-error"></p>
Regards, Mark.
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