As Google pretty much ignores them anyway, and I assume that you are trying to rank in Google, then no, it makes no difference. Other SE's do make some use of them still. The only thing G uses is the description (sometimes - it still can override this depending on it's mood lol ) and title.
As an aside, we always use a separate SEO component like JoomSEF anyway so can tweak settings on a per page basis regardless of the content.